some NEW DNA facts

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  • Dimko-piperkata
    Senior Member
    • Sep 2008
    • 1876

    some NEW DNA facts

    Distribution of killer cell immunoglobulinlike receptors in the Macedonian population

    Abstract


    The aim of this study was to analyze killer immunoglobulinlike receptor (KIR) gene polymorphism in the Macedonian population. The study sample consists of 214 healthy unrelated individuals, aged 20–35 years. All individuals are of Macedonian origin and nationality, and residents of different geographic regions. The population genetics analysis package, Arlequin, was used for analysis of the data. We found that all 16 KIR genes were observed in the Macedonian population and framework genes KIR3DL3, KIR2DL4, and KIR3DL2 were present in all individuals. A total of 56 different KIR genotypes were found in the Macedonian population, based on the presence of 16 KIR genes. Neighbor-joining phylogenetic tree, constructed on the basis of standard genetic distances of KIR genes, shows that Macedonian population is in the same cluster with England West Midlands Indian Asian, Brazil SouthEast Caucasian, Romania Caucasians, Spain Basque, England West Midlands Caucasian, France Reunion, and Spain Granada populations. The frequency of KIR loci in Macedonian population shares several general features with other Caucasoid populations studied before.
    1) Macedonians belong to the "older" Mediterranean substratum...
    2) Macedonians are not related with geographically close Greeks, who do not belong to the "older" Mediterranenan substratum...
  • Voltron
    Banned
    • Jan 2011
    • 1362

    #2
    Never was one for using DNA as an ethnic qualifier but just for arguments sake you can see that they link the Slavic linguistic countries below the same. Greece didnt participate probably due to the political problems we have and the mistrust between the two countries.

    SKOPJE -- A six-year long DNA research of the Balkan peoples conducted by Skopje Forensics Medicine Institute has showed remarkable resemblance among them.

    “The analysis of the data has showed that residents of Macedonia have the most similar DNA with Bulgarians and Serbs, Croats with Bosnian and Serbian population while Kosovo Albanians have the fewest similarities with the others,” says Forensics Medicine Institute’s Dr Zlatko Jakovski.


    Comment

    • DedoAleko
      Member
      • Jun 2009
      • 969

      #3
      Originally posted by Voltron View Post
      Never was one for using DNA as an ethnic qualifier but just for arguments sake you can see that they link the Slavic linguistic countries below the same. Greece didnt participate probably due to the political problems we have and the mistrust between the two countries.

      SKOPJE -- A six-year long DNA research of the Balkan peoples conducted by Skopje Forensics Medicine Institute has showed remarkable resemblance among them.

      “The analysis of the data has showed that residents of Macedonia have the most similar DNA with Bulgarians and Serbs, Croats with Bosnian and Serbian population while Kosovo Albanians have the fewest similarities with the others,” says Forensics Medicine Institute’s Dr Zlatko Jakovski.


      http://www.b92.net/eng/news/society-...2&nav_id=78407
      That Dr you (mis)quote was actually on tv a week ago and he stated he was misquoted and that this research is not about the origin and similarities of people, and that for that kind of research takes more time and money.
      “Јаковски додава дека за истражување на потеклото на народите и за нивните меѓусебни сличности и разлики се неопходни многу повеќе пари и време.”-izvor: http://www.plusinfo.mk/vest/30645/OB...sancite#tabs-2
      And I found his email and phone number, so somebody can ask him: [email protected]
      Izvor: http://www.academicjournals.org/JCPF...%20et%20al.htm

      Comment

      • Voltron
        Banned
        • Jan 2011
        • 1362

        #4
        Oetzi the Iceman's nuclear genome gives new insights

        New clues have emerged in what could be described as the world's oldest murder case: that of Oetzi the "Iceman", whose 5,300-year-old body was discovered frozen in the Italian Alps in 1991.

        Oetzi's full genome has now been reported in Nature Communications.

        It reveals that he had brown eyes, "O" blood type, was lactose intolerant, and was predisposed to heart disease.

        They also show him to be the first documented case of infection by a Lyme disease bacterium.

        Analysis of series of anomalies in the Iceman's DNA also revealed him to be more closely related to modern inhabitants of Corsica and Sardinia than to populations in the Alps, where he was unearthed.
        'Really exciting'

        The study reveals the fuller genetic picture as laid out in the nuclei of Oetzi's cells.

        This nuclear DNA is both rarer and typically less well-preserved than the DNA within mitochondria, the cell's "power plants", which also contain DNA.
        Oetzi reconstruction (South Tyrol Museum of Archaeology/EURAC/Marco Samadelli-Gregor Staschitz) A reconstruction shows what Oetzi may have looked like before an arrow felled him

        Oetzi's mitochondrial DNA had already revealed some hints of his origins when it was fully sequenced in 2008.

        Albert Zink, from the Eurac Institute for Mummies and the Iceman in Bolzano, Italy, said the nuclear DNA study was a great leap forward in one of the most widely studied specimens in science.

        "We've been studying the Iceman for 20 years. We know so many things about him - where he lived, how he died - but very little was known about his genetics, the genetic information he was carrying around," he told BBC News.

        He was carrying around a "haplotype" that showed his ancestors most likely migrated from the Middle East as the practice of formal agriculture became more widespread.


        It is probably this period of transition to an agrarian society that explains Oetzi's lactose intolerance.

        Prof Zink said that next-generation "whole-genome" sequencing techniques made the analysis possible.

        "Whole-genome sequencing allows you to sequence the whole DNA out of one sample; that wasn't possible before in the same way.

        "This was really exciting and I think it's just the start for a longer study on this level. We still would like to learn more from this data - we've only just started to analyse it."

        The picture below doesnt look like a middle easterner at all.

        Comment

        • vicsinad
          Senior Member
          • May 2011
          • 2337

          #5
          Originally posted by Voltron View Post
          The picture below doesnt look like a middle easterner at all.

          That's because his ancestors migrated well over 5,000 years ago. People's physical features evolve over time. All homo sapiens evolved in Africa -- but we don't look like we came from Africa. That's because: a) natural selection and other factors caused features to change; b) the color of the skin of the original homo sapiens that evolved in Africa most likely was not black and rather more like that of the skin color (not hair color) of modern apes. So the Middle Easterners over 5,000 years ago did not have the same exact physical attributes as they do today...or, because we don't know when his ancestors arrived to Italy (which we will assume is well over 5,300 years ago...possibly up to 10,000 years ago), it is likely that his resulting physical features are a result of adaptations to European mountain climate and etc.

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